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Image Search Results
Journal: Biomolecules
Article Title: Palmitic Acid Esterification Boosts Epigallocatechin Gallate’s Immunomodulatory Effects in Intestinal Inflammation
doi: 10.3390/biom15081208
Figure Lengend Snippet: Dot plots of representative pro-inflammatory (CD86-Coralite ® Plus 647, M1) and propidium iodide double stains of M0 macrophages (differentiated from THP-1 monocytic cells treated with Phorbol-Myristate Acetate) exposed to pro-inflammatory growth media of Caco-2 cells in the presence/absence of epigallocatechin gallate and palmitoyl epigallocatechin gallate. Distinct lowercase letters indicate significantly different values at p < 0.05 according to one-way analyses of variance (ANOVA) and Duncan’s multiple range test ( n = 3).
Article Snippet: CoraLite
Techniques:
Journal: Molecular Cancer Research
Article Title: Neoadjuvant Chemotherapy Induces IL34 Signaling and Promotes Chemoresistance via Tumor-Associated Macrophage Polarization in Esophageal Squamous Cell Carcinoma
doi: 10.1158/1541-7786.mcr-20-0917
Figure Lengend Snippet: Figure 1. Increased infiltration and polarized differentiation of TAMs by NAC in ESCC. A, Schematic illustration of the experimental design. B, Representative IHC images of CD163 expression in ESCC specimens from patients who received NAC [NAC (þ)] and did not receive NAC [NAC ()]. Scale bars, 100 mm; original magnification 200. Pre-, Pre-NAC; Post-, Post-NAC. C, Comparison of the number of CD163þ TAMs between biopsy and surgically resected ESCC specimens in NAC () (n ¼ 12) and NAC (þ) (n ¼ 33). D, Comparison of the number of CD163þ TAMs between NAC () (n ¼ 12) and NAC (þ) (n ¼ 33) in biopsy and surgically resected ESCC specimens. E, Comparison of the intensities of CD163 expression between biopsy and surgically resected ESCC specimens in NAC () (n ¼ 12) and NAC (þ) (n ¼ 33). F, Comparison of the intensities of CD163 expression between NAC () (n ¼ 12) and NAC (þ) (n ¼ 33) in biopsy and surgically resected ESCC specimens. G, Representative IHC images of the expression of CD163, CD3, CD8, CD105, E-cadherin, and vimentin in surgically resected ESCC specimens from patients who received NAC [NAC (þ)]. Scale bars, 100 mm; original magnification 200. Post-, Post-NAC. H, Correlations between the number of CD163þ cells and the number of CD3þ TILs, the number of CD8þ TILs, CD105þ microvessel counts, E-cadherin staining score, or Vimentin staining score in surgically resected ESCC specimens of NAC (þ) (n ¼ 33). , P < 0.01; , P < 0.001; , P < 0.0001.
Article Snippet: Reagents used in this study were acquired from the indicated suppliers: 5-FU, KU-55933, and VE-821 (Merck Sigma-Aldrich); cisplatin (FUJIFILM Wako Pure Chemical Corporation); antihuman IL34 antibody [1D12] (ab101443), anti-M-CSF antibody [EP1179Y] (ab52864; Abcam); Novocastra Liquid Mouse Monoclonal Antibody CD163 (NCL-L-CD163; Leica Biosystems);
Techniques: Expressing, Comparison, Staining